论著

盐酸艾司氯胺酮联合丙泊酚在小儿眼睑肿物刮除术中的临床应用

Clinical application of esmketamine hydrochloride combined with propofol in curettage of eyelid tumors in children

:707-713
 
目的:观察盐酸艾司氯胺酮联合丙泊酚在小儿眼睑肿物刮除术中的临床应用效果,评价盐酸艾司氯胺酮联合丙泊酚在小儿眼睑肿物刮除术麻醉中的有效性和安全性。方法:选择2020年11月至2021年7月在佛山市第二人民医院择期行眼睑肿物刮除术的70例患儿,随机分为A组和B组,每组35例。A组采用七氟烷联合丙泊酚复合麻醉,B组采用盐酸艾司氯胺酮联合丙泊酚复合麻醉。记录两组患儿诱导时间、手术时间、苏醒时间、复苏总时间;监测麻醉前、麻醉后5 min、手术开始前、手术结束后患儿血流动力学及呼吸频率变化;记录两组患儿苏醒后即刻、返回病房即刻的东安大略儿童医院疼痛评分量表(Children’s Hospital of Eastern Ontario Pain Scale,CHEOPS)疼痛评分、躁动评分、恶心呕吐评分。结果:两组患儿麻醉诱导时间比较差异无统计学意义(P>0.05);两组患儿麻醉过程中血流动力学水平、呼吸频率差异无统计学意义(P>0.05);B组患儿苏醒时间、复苏总时间均明显低于A组(P<0.05);B组患儿苏醒后即刻及返回病房即刻CHEOPS疼痛评分、躁动评分、恶心呕吐评分均明显低于A组(P<0.05)。另外,B组患儿术后出现恶心呕吐概率低于A组(P<0.05)。结论:盐酸艾司氯胺酮联合丙泊酚应用于小儿眼睑肿物刮除术麻醉,能提供良好麻醉镇痛效果,降低躁动反应和恶心呕吐的发生
Objective: To investigate the anesthetic effect and to evaluate the efficacy and safety of combination application of esketamine and propofol in curettage of eyelid tumors of children. Methods: This study selected 70 children who underwent elective eyelid tumor curettage in Foshan Second People’s Hospital from November 2020 to July 2021. They were randomly divided into group A and group B, with 35 cases in each group. Patients in Group A were anesthetized with sevoflurane combined with propofol. Patients in Group B were anesthetized with esketamine combined with propofol. The anesthetic induction time, operation time, recovery time and total recovery time of the two groups were recorded. The haemodynamics and respiratory frequency changes of patients were being monitored before anesthesia, 5 minutes after anesthesia, before the operation and after the operation. The scores of Children’s Hospital of Eastern Ontario Pain Scale (CHEOPS) pain, agitation and nausea and vomiting were recorded immediately after the patients awakened and were sent back to the ward. Results: There was no significant difference in anesthesia induction time between the two groups (P>0.05). There was also no significant difference in the haemodynamics and respiratory frequency changes during the anaesthetic process between the two groups (P>0.05). The recovery time and total recovery time in group B were significantly lower than those in group A (P<0.05). The scores of CHEOPS pain, agitation and nausea and vomiting in group B were significantly lower than those in group A immediately after the patients awakened and were sent back to the ward (P<0.05). Besides, the probability of nausea and vomiting after curettage of eyelid tumors was lower in group B than in group A (P<0.05). Conclusion: Combination application of esketamine and propofol in curettage of eyelid tumors of children can provide good anesthetic and analgesic effect and reduce the occurrence of restlessness, nausea and vomiting.
小儿眼病专题

人工智能与婴幼儿眼病的研究进展

Advances in application of artificial intelligence in infantile eye diseases

:799-805
 
近年来人工智能(artificial intelligence,AI)技术在医学领域的应用发展迅猛,尤其在眼科领域,成果显著,极大地提高了相关影像数据的诊断效率,推动了该领域研究的进展。然而,大多数AI的应用都集中于成人眼病,在婴幼儿眼病方向的研究较少。究其原因,可能是婴幼儿眼部影像数据采集配合度低,部分影像设备应用受限,且相关领域专业眼科医生数量匮乏。然而,婴幼儿期是视觉发育最重要的阶段,也是出生缺陷早期筛防诊治的重灾区,对患儿的视觉发展具有长远且重要的影响,亟需AI相关产品提高婴幼儿眼病筛查效率,缓解医疗资源不足的现状。本文将对近年AI在婴幼儿眼病领域的研究应用现状、进展及存在的相关问题进行综述。
In recent years, the application of artificial intelligence (AI) in medicine, especially in ophthalmology, has developed rapidly with remarkable results. This has greatly improved the diagnostic efficiency of relevant imaging data and promoted further research in this field. However, most applications of AI are focused on adult eye diseases, and few studies have addressed infantile eye diseases. This may be because of the non-cooperative nature of infants, the limited availability of imaging equipment in infants, and the lack of pediatric ophthalmologists. Infancy is the most important stage of vision development. Disturbance during this period have a profound and lasting influence on vision development. Hence, early screening, diagnosis, and treatment of birth defects is important. AI-related products, which improves the efficacy of infant eye disease screening, are urgently needed. This paper reviews the current status, progress, and existing problems of recent research related to application of AI in infantile eye diseases.
其他期刊
  • 眼科学报

    主管:中华人民共和国教育部
    主办:中山大学
    承办:中山大学中山眼科中心
    主编:林浩添
    主管:中华人民共和国教育部
    主办:中山大学
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  • Eye Science

    主管:中华人民共和国教育部
    主办:中山大学
    承办:中山大学中山眼科中心
    主编:林浩添
    主管:中华人民共和国教育部
    主办:中山大学
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中山眼科



中山大学