本文对7例正常人眼前房角小梁网进行了组织化学——酸性粘多糖及超微结构的研究。结果表明人类正常眼前房角小梁中存在酸性粘多糖,以内皮网处较多,大部分可被透明质酸酶消化。小梁带中螺旋纤维可能是小梁网柔韧性的结构基础,小梁带基板层与小梁带内皮细胞胞浆存在密切联系,小梁内皮细胞间的连接,可能对防止小梁带受外界因素影响而发生位移有一定稳固作用,内皮网间质中存在Ⅰ、Ⅱ型斑状物及胶原成分,39岁以下眼中含量较少,老年眼中较多。Schlemm 氏管内壁内皮细胞胞浆中液泡是房水排出的细胞内途径,证实了本文作者1963年提出的论点。

Histochemical and ultrastructural studies of the trabecular meshwork (TM) of 7 normal human eyes were carried out. The age of this group ranged between 20-70 years. Histochemical results showed that acid mucopolysaccharides existed in the TM of normal eyes, especially in the endothelial meshwork portion. Most of the acid mucopoly-saccharides were digestible by testicular hyaluronidase. The ultrastructural study indicated the following: 1. The spiral fibrils surrounding the collagen core of TM were spaced unequally in spiral distance and might wind loosely or tightly. This structure might be the anatomic basis of the flexibility of the trabeculae, 2. The discontinuous cytoplasmic membrane of the endothelium and the extention of the basal lamina to the endothelial cytoplasm as a process-like structure might imply that there were substances exchanged between the endothelial cells and the basal lamina of the trabeculae. 3. The structures known as tongue-in-groove and interdigitation joints were desmosomes or gap junctions between the adjacent cell membrane. These two junctional structures might act as stabilizers to prevent trabecular bands from moving when effected by outer environment. 4. The vacuoles within the cytoplasm of the endothelial cell lining the inner wall of Schlemm's canal might indicate that the aqueous outflow passes through intracellular path-way. This evidence confirmed our suggestion in 1963 which is consistent with many authors' idea.