Glaucoma is the leading cause for irreversible blindness in the world, which is associated with progressive retinal ganglion cell apoptosis. The changes in optic disc structure have been found before visual function variation in many patients. Detecting changes in the structure of the optic disc R is crucial for the diagnosis of early glaucoma. Recently, a new optic disc parameter, Bruce's membrane opening minimum rim width (BMO-MRW) , has been increasingly widely used in clinical practice and become a popular parameter in current clinical research. Retinal nerve fiber layer (RNFL)is an important diagnostic indicator for glaucoma. Many studies indicated that BMO-MRW and RNFL have similar diagnostic performance. In some glaucoma cases with unclear optic disc structure, such as myopia and abnormal optic disc, BMO-MRW provides better diagnostic parameter than RNFL does. It also plays a role in monitoring the changes of glaucoma. Some studies also stated the limitation of the application of this parameter in glaucoma postoperative follow-up. This artice reviews the clinical application of BMO-MRW in diagnosis and follow-up of open-angle glaucoma,providing reference for clinical practicers.
