息肉状脉络膜血管病变(polypoidal choroidal vasculopathy,PCV)是亚洲人群中常见的致盲性眼病，发生大出血并发症后严重危害视力且预后差。PCV大出血包括视网膜下出血(subretinal hemorrhage,SRH)和玻璃体积血(vitreous hemorrhage,VH)。SRH的危险因素包括较长病程、簇型PCV、息肉状病灶不消退、合并视网膜色素上皮脱离；其治疗方式包括抗血管内皮生长因子药物、光动力疗法、激光、玻璃体腔注气、眼内注射组织纤溶酶原激活剂、玻璃体切割术或联合治疗等方式，其中，黄斑中心凹是否受累和出血时间是影响治疗方式选择的主要因素。发病年龄较大、白细胞计数较高、天门氨酸转移酶和丙氨酸转氨酶的比值较高、活化部分凝血活酶时间较长、曾行光动力疗法、有玻璃体腔注药治疗史、SRH面积大、出现视网膜色素上皮脱离的PCV患者发生VH的风险高。浓厚的VH通常需行玻璃体切割术，其手术时机和手术方式的选择是临床关注的焦点。鉴于目前PCV大出血的危险因素尚不完全明确、治疗方面也尚未形成共识，需要开展相关临床研究，提供更多依据。

Polypoidal choroidal vasculopathy (PCV) is a common blinding disease in Asian populations. Massive hemorrhage complications secondary to PCV includes subretinal hemorrhage (SRH) and vitreous hemorrhage (VH). The risk factors for SRH include a long duration, clustered PCV, non-regression of polyp lesions and presented with retinal pigment epithelial detachment. The treatments for SRH including anti-vascular endothelial growth factor drugs, photodynamic therapy, laser, vitreous pneumatic displacement, intravenously injected tissue plasminogen activator, vitrectomy and combination therapy. Whether macular fovea is involved and the time since bleeding onset are the main factors afecting the choice of treatment for SRH. Older age of onset, higher white blood cell count, higher aspartate amino transferase and alanine amino transferase ratio, longer activated partial thromboplastin time retinal pigment epithelium detachment, photodynamic therapy history, intravitreal injection history larger SRH area and presented with retinal pigment epithelial detachment were associated with higher risk of VH. PCV patients with massive VH should be treated with vitrectomy, while the timing and technique of operation should be paid atention to. At present, the risk factors of PCV massive bleeding are not completedly clear, and its treatment methods are diverse, which requires a large number of studies to prove its efectiveness and establish expert diagnosis and treatment consensus.

目的：探讨白内障人群角膜屈光力(corneal refractive power,CRP)的分布特点及与眼生物学参数的相关因素分析。方法：回顾性横断面研究福州眼科医院2019年3月至2022年7月就诊的40岁以上白内障人群共23035眼，使用OA-2000测量其眼轴(axial length,AL)、CRP、前房深度(anterior chamber depth,ACD)、晶状体厚度(lens thickness,LT)、角膜水平直径即白到白(white-to-white,W T W)、中央角膜厚度(central corneal thickness,CCT)。绘制各眼生物学参数及年龄Spearman相关性热力图，绘制CRP与AL、CRP与WTW散点拟合图。将CRP与上述参数及年龄进行Spearman相关性分析，分段数据的线性关系使用Pearson分析及线性回归分析。结果：白内障人群CRP为(44.36±1.52)D，在总体数据中CRP与AL为非线性相关；但在分段数据中存在线性相关：当AL≤25.06 mm，CRP与AL负线性相关(R2 =0.397，P<0.001)；当AL>25.06 mm，CRP与AL正线性相关(R2 =0.045，P<0.001)；无论AL长短，CRP与WTW、CCT均呈负相关。在总体数据中，CRP与WTW也存在非线性关系；但在分段数据中存在线性相关：当10.52 mm≤WTW≤12.46 mm，CRP与WTW负线性相关(R2 =0.149，P<0.001)，并与AL、ACD、CCT呈负相关。结论：CRP与AL、WTW呈非线性相关，使用CRP优化计算人工晶状体(intraocular lens,IOL)屈光力时需适当考虑AL、WTW与CRP的相关性。

Objective: To investigate the distribution characteristics of corneal refractive power (CRP), and analyze the correlation between corneal refractive power and ocular biometric parameters in cataract patients. Methods: A retrospective cross-sectional study was conducted on 2,3035 eyes of cataract patients over 40 years old, who visited Fuzhou Eye Hospital during the period between March 2019 and July 2022. The subjects' examination results of axial length (AL), corneal refractive power (CRP), anterior chamber depth (ACD), lens thickness (LT), horizontal corneal diameter (WTW), central corneal thickness (CCT) were measured by OA-2000. Spearman correlation thermograms of bilological parameters and age for each eyes were worked out. The plot scatter fitting plots of CRP and AL, CRP and WTW were made. Spearman correlation analysis was made among CRP, above-mentioned parameters and age. Linear relationships of the segmented data were analyzed with Pearson and linear regression analysis. Results: In the cataract patients, CRP was (44.36 ± 1.52) D. There was a non-linear correlation between CRP and AL in the total data. However, there was a linear relationship in the segmented data. When AL ≤ 25.06 mm, CRP was negatively linearly correlated with AL (R2 =0.397, P<0.001). When AL>25.06 mm, CRP was weakly positively correlated with AL (R2 =0.045, P<0.001). Regardless of the length of AL, CRP was negatively correlated with WTW and CCT. There was also a nonlinear relationship between CRP and WTW in the total data. But there was a linear correlation in the segmented data.When 10.52 mm ≤ WTW ≤ 12.46 mm, the negative linear correlation was found between CRP and WTW (R2 =0.149, P<0.001), while there was negative correlation among CRP, AL, ACD, and CCT. Conclusion: There is a non-linear correlation among CRP, AL and WTW. To optimize the calculation of intraocular lens (IOL) refractive power with CRP, it is necessary to consider the correlation between AL, WTW, and CRP.

玻璃体切割术是目前临床上常见的眼科手术之一，其应用广泛，且具有良好的治疗效果，但术后仍会出现各种并发症，眼压升高便是其中常见的一种。玻璃体切割术后眼压升高的病因复杂多样，术前原发病的不同、术中处理方式的差异以及术后并发症均可引起眼压升高，根据不同的病因可以选用更合适的治疗方法。早期的眼压升高较易控制，主要采用药物及激光治疗，晚期眼压升高导致继发性青光眼则相对复杂，以手术治疗为主。该文主要对玻璃体切割术后高眼压的原因分析及治疗进展进行综述。

Pars plana vitrectomy is one of the common ophthalmic surgeries in clinic practice currently, which is widely used with good therapeutic effect. However, various complications may still occur after operation. Elevated intraocular pressure is one of common complications. The causes of postoperative ocular hypertension are complex and diverse. Elevated intraocular pressure could be caused by different preoperative primary diseases, intraoperative management methods,and postoperative complication. More appropriate treatment methods can be selected based on different causes. Early elevated intraocular pressure iseasier to control and is mainly treated with medicine and laser. Late elevated intraocular pressure leads to secondary glaucoma, which is relatively complex and mainly treated with surgery. This review mainly states causes and treatment progress of high intraocular pressure after vitrectomy.

目的：了解湿性老年性黄斑变性(age-related macular degeneration,AMD)患者自我感受负担(self-perceived burden,SPB)现状及其影响因素。方法：采用方便抽样法选取2021年1月至11月在中山大学中山眼科中心就诊的204例湿性AMD患者为研究对象，采用一般资料调查表、SPB量表、家庭支持自评量表、医学应对问卷对其进行测评。结果：患者SPB得分是(21.98±6.68)分，总体属于轻度SPB。湿性AMD患者的SPB水平与家庭支出(r=?0.326, P<0.001)和面对应对(r=?0.365, P<0.001)呈负相关，与回避(r=0.456, P<0.001)及屈服(r=0.310, P<0.001)应对方式呈正相关性。多重线性回归显示，独居、高龄、自费、双眼患病及采用回避应对的患者的SPB更高，而高文化水平、高家庭支持的患者SPB较轻。结论：湿性AMD患者有轻度SPB，但仍存在改善空间，医护工作者在工作中应重点关注高龄、文化程度低、家庭收入低、自费、独居、双眼患病及低视力的患者，及时进行心理疏导，减轻患者的SPB水平。

Objective: To understand the current status and influencing factors of self-preceived burden (SPB) in patients with wet age-related macular degeneration (AMD). Methods: 204 patiens with wet AMD who were treated in Zhongshan Ophthalmic Center, Sun Yat-sen University from January to November 2021 were enrolled as the study subjects with convenience sampling method. A general information questionnaire, SPB scale, family support self-assessment scale, and medical coping questionnaire were collected from the subjects for assessment. Results: The patient’s SPB score was 21.98±6.68, which is generally mild SPB. The SPB level of patients with wet AMD was negatively correlated with family support (r=-0.326, P<0.001) and coping (r=?0.365, P<0.001), and were positively correlated with avoidance (r= 0.456,P<0.001), and surrender (r=0.310, P<0.001) coping style. Multiple linear regression showed that the patients who lived alone, were elder and self-funded, had binoclur diseases and used avoidance coping, had higher SPB. While the patients with high education and family support had lower SPB. Conclusions: It is still needed to pay attention to the patients with AMD having mild SPB. Medical workers should focus on patients with elder age, low education level, low family income, self-funded, living alone, binocular disease and low vision in their work, and provide timely psychological counseling to reduce the SPB level of patients.

目的：观察学龄儿童的近视进展情况，分析近视进展的危险因素。方法：于2014年纳入温州2所小学二、三年级近视儿童，每年随访1次，直至小学毕业。检查内容包括非睫状肌麻痹主觉验光、双眼视功能检查(隐斜、调节性集合/调节、正负相对调节、正负融像性聚散)和问卷调查。采用无序多分类logistic回归分析近视进展速度的危险因素。结果：共纳入152名近视儿童[年龄7~9岁，95名(62.5%)男性]，初始屈光度为?1.30±0.95屈光度(diopter，D)，年近视进展量为?0.68±0.35 D。回归分析表明：与慢速组相比(年近视进展量>?0.50 D)，中速组(?1.00 D<年近视进展量≤?0.50 D)与快速组(年近视进展量≤?1.00 D)中初始屈光度≤?1.00 D的儿童占比更大(中速组：OR=3.51，P=0.003；快速组：OR=3.29，P=0.044)，快速组中女性占比更大(OR=4.52，P=0.012)，基线双眼视功能参数在不同组间差异均无统计学意义(均P>0.05)。结论：学龄儿童近视进展速度与性别、初始屈光度相关，与基线双眼视功能无关。女孩、初始近视程度大(7~9岁时，屈光度≤?1.00 D)的儿童近视进展快。

摘要英文

目的：观察学龄儿童的近视进展情况，分析近视进展的危险因素。方法：于2014年纳入温州2所小学二、三年级近视儿童，每年随访1次，直至小学毕业。检查内容包括非睫状肌麻痹主觉验光、双眼视功能检查(隐斜、调节性集合/调节、正负相对调节、正负融像性聚散)和问卷调查。采用无序多分类logistic回归分析近视进展速度的危险因素。结果：共纳入152名近视儿童[年龄7~9岁，95名(62.5%)男性]，初始屈光度为?1.30±0.95屈光度(diopter，D)，年近视进展量为?0.68±0.35 D。回归分析表明：与慢速组相比(年近视进展量>?0.50 D)，中速组(?1.00 D<年近视进展量≤?0.50 D)与快速组(年近视进展量≤?1.00 D)中初始屈光度≤?1.00 D的儿童占比更大(中速组：OR=3.51，P=0.003；快速组：OR=3.29，P=0.044)，快速组中女性占比更大(OR=4.52，P=0.012)，基线双眼视功能参数在不同组间差异均无统计学意义(均P>0.05)。结论：学龄儿童近视进展速度与性别、初始屈光度相关，与基线双眼视功能无关。女孩、初始近视程度大(7~9岁时，屈光度≤?1.00 D)的儿童近视进展快。

摘要英文

目的：观察学龄儿童的近视进展情况，分析近视进展的危险因素。方法：于2014年纳入温州2所小学二、三年级近视儿童，每年随访1次，直至小学毕业。检查内容包括非睫状肌麻痹主觉验光、双眼视功能检查(隐斜、调节性集合/调节、正负相对调节、正负融像性聚散)和问卷调查。采用无序多分类logistic回归分析近视进展速度的危险因素。结果：共纳入152名近视儿童[年龄7~9岁，95名(62.5%)男性]，初始屈光度为?1.30±0.95屈光度(diopter，D)，年近视进展量为?0.68±0.35 D。回归分析表明：与慢速组相比(年近视进展量>?0.50 D)，中速组(?1.00 D<年近视进展量≤?0.50 D)与快速组(年近视进展量≤?1.00 D)中初始屈光度≤?1.00 D的儿童占比更大(中速组：OR=3.51，P=0.003；快速组：OR=3.29，P=0.044)，快速组中女性占比更大(OR=4.52，P=0.012)，基线双眼视功能参数在不同组间差异均无统计学意义(均P>0.05)。结论：学龄儿童近视进展速度与性别、初始屈光度相关，与基线双眼视功能无关。女孩、初始近视程度大(7~9岁时，屈光度≤?1.00 D)的儿童近视进展快。

摘要英文

目的：观察学龄儿童的近视进展情况，分析近视进展的危险因素。方法：于2014年纳入温州2所小学二、三年级近视儿童，每年随访1次，直至小学毕业。检查内容包括非睫状肌麻痹主觉验光、双眼视功能检查(隐斜、调节性集合/调节、正负相对调节、正负融像性聚散)和问卷调查。采用无序多分类logistic回归分析近视进展速度的危险因素。结果：共纳入152名近视儿童[年龄7~9岁，95名(62.5%)男性]，初始屈光度为?1.30±0.95屈光度(diopter，D)，年近视进展量为?0.68±0.35 D。回归分析表明：与慢速组相比(年近视进展量>?0.50 D)，中速组(?1.00 D<年近视进展量≤?0.50 D)与快速组(年近视进展量≤?1.00 D)中初始屈光度≤?1.00 D的儿童占比更大(中速组：OR=3.51，P=0.003；快速组：OR=3.29，P=0.044)，快速组中女性占比更大(OR=4.52，P=0.012)，基线双眼视功能参数在不同组间差异均无统计学意义(均P>0.05)。结论：学龄儿童近视进展速度与性别、初始屈光度相关，与基线双眼视功能无关。女孩、初始近视程度大(7~9岁时，屈光度≤?1.00 D)的儿童近视进展快。

摘要英文

目的：观察学龄儿童的近视进展情况，分析近视进展的危险因素。方法：于2014年纳入温州2所小学二、三年级近视儿童，每年随访1次，直至小学毕业。检查内容包括非睫状肌麻痹主觉验光、双眼视功能检查(隐斜、调节性集合/调节、正负相对调节、正负融像性聚散)和问卷调查。采用无序多分类logistic回归分析近视进展速度的危险因素。结果：共纳入152名近视儿童[年龄7~9岁，95名(62.5%)男性]，初始屈光度为?1.30±0.95屈光度(diopter，D)，年近视进展量为?0.68±0.35 D。回归分析表明：与慢速组相比(年近视进展量>?0.50 D)，中速组(?1.00 D<年近视进展量≤?0.50 D)与快速组(年近视进展量≤?1.00 D)中初始屈光度≤?1.00 D的儿童占比更大(中速组：OR=3.51，P=0.003；快速组：OR=3.29，P=0.044)，快速组中女性占比更大(OR=4.52，P=0.012)，基线双眼视功能参数在不同组间差异均无统计学意义(均P>0.05)。结论：学龄儿童近视进展速度与性别、初始屈光度相关，与基线双眼视功能无关。女孩、初始近视程度大(7~9岁时，屈光度≤?1.00 D)的儿童近视进展快。

摘要英文

目的：观察学龄儿童的近视进展情况，分析近视进展的危险因素。方法：于2014年纳入温州2所小学二、三年级近视儿童，每年随访1次，直至小学毕业。检查内容包括非睫状肌麻痹主觉验光、双眼视功能检查(隐斜、调节性集合/调节、正负相对调节、正负融像性聚散)和问卷调查。采用无序多分类logistic回归分析近视进展速度的危险因素。结果：共纳入152名近视儿童[年龄7~9岁，95名(62.5%)男性]，初始屈光度为?1.30±0.95屈光度(diopter，D)，年近视进展量为?0.68±0.35 D。回归分析表明：与慢速组相比(年近视进展量>?0.50 D)，中速组(?1.00 D<年近视进展量≤?0.50 D)与快速组(年近视进展量≤?1.00 D)中初始屈光度≤?1.00 D的儿童占比更大(中速组：OR=3.51，P=0.003；快速组：OR=3.29，P=0.044)，快速组中女性占比更大(OR=4.52，P=0.012)，基线双眼视功能参数在不同组间差异均无统计学意义(均P>0.05)。结论：学龄儿童近视进展速度与性别、初始屈光度相关，与基线双眼视功能无关。女孩、初始近视程度大(7~9岁时，屈光度≤?1.00 D)的儿童近视进展快。

摘要英文