Aims: To analyze the characteristics and trends of non-tumor-related eye removal in Southern China from 2009 to 2018. Methods: Inpatient data from Zhongshan Ophthalmic Center were examined to identify trends and characteristics of non-tumorous enucleation/evisceration. The Chi-square test assessed differences in age, gender, and etiology, while linear regression analyzed the significance of trends from 2009 to 2018 across subgroups. The nonquadratic Mann-Kendall test evaluated the trends in etiology and types of ocular injuries. Results: A total of 1824 patients (mean age 28 years, SD 19.2) underwent non-tumor-related eye removal during the study period. The majority were male (73.1%), with ocular trauma (72.3%) and corneal perforation (7.7%) being the leading causes. Work-related injuries accounted for 30.5% of ocular trauma, showing a moderate increase over the decade. However, no statistically significant trends were observed in the etiology or specific causes of ocular trauma. Conclusions: The rates of non-tumorous eye removal remained stable from 2009 to 2018. Ocular trauma was the predominant non-tumorous cause of enucleation or evisceration in Southern China. Translational Relevance: The findings highlight the need for preventive measures against work-related injuries leading to enucleation and the importance of rigorous childcare to mitigate the risk of eye removal due to trauma.
Background: To measure the anterior and posterior segment structural features of acute primary angle-closure (APAC) eyes.
Methods: A total of 36 subjects with unilateral APAC were recruited in this study. The ocular biometric characteristics were measured by anterior segment optical coherence tomography (AS-OCT) and swept source optical coherence tomography (SS-OCT), respectively at baseline, 2 weeks, and 1 month after surgical intervention.
Results: At baseline, when compared with the fellow eyes, APAC-affected eyes showed significantly greater corneal thickness (P=0.004), shallower anterior chamber depth (ACD) (P<0.001), smaller anterior chamber area (ACA) (P=0.013), angle opening distance at 750 μm from the scleral spur (AOD750) (P=0.002), trabecular–iris space area at 750 μm from the scleral spur (TISA750) (P=0.033), angle recess area (ARA) (P=0.014), and iris area (IARE) (P=0.003), less iris curvature (ICURVE) (P=0.003), and larger lens vault (LV) (P=0.030). After intervention, the corneal thickness was significantly decreased at 1 month (P<0.001), while ACD, ACA, and AOD750 were significantly increased at 2 weeks and 1 month (all P<0.017). Changes in ACD were correlated with decreasing LV (P<0.05). The posterior segment parameters did not change over the 4-week period.
Conclusions: When compared with the fellow eyes, APAC-affected eyes had greater corneal thickness, shallower anterior chamber, narrower angle, less ICURVE, and larger LV. After intervention, the corneal thickness was decreased, while the shallower anterior chamber was relieved to some extent.
